Correlation of CD40 and DPP-4 Concentration With Corrected TIMI Frame Count in Patients With Coronary Slow Flow

Introduction: Microvascular and endothelial disorders play a significant role in the pathophysiology of coronary slow flow phenomenon (CSFP). However, according to previous studies, etiology CSFP is not completely understood. As CD40 dipeptidyl peptidase-4 (DPP-4) are reported an important atherosclerosis process as well microvascular dysfunction, this study evaluated these two biomarkers CSFP. Methods: One-hundred twenty-nine volunteers who were candidates for angiography fulfilled inclusion criteria selected, including 29 patients with artery diseases (CADs) which had less than 50% stenosis (CAD+,<50%) without CSF, 22 CAD+patients 50-90% (CAD+, 50%-90%) 16 CSF their arteries, 40 healthy individuals controls. The serum levels DPP-4 measured by enzyme-linked immunosorbent assay kit. Results: There was no correlation between concentration thrombosis myocardial infarction (TIMI) frame count (P=0.571). significantly higher values (P=0.022). Moreover, different vessels did exhibit any relation TIMI score (P=0.763). Conclusion: In present study, found concentrations mean corrected (CTFC). Accordingly, further studies larger population sizes needed investigate